Latest Research


Down syndrome

1. Iizuka M, Abe M, Shiiba K, Sasaki I, Sato Y. Down syndrome candidate region 1,a downstream target of VEGF, participates in endothelial cell migration and angiogenesis. J Vasc Res. 2004 Jul-Aug;41(4):334-44. Epub 2004 Jul 15.

2. Pfister SC, Machado-Santelli GM, Han SW, Henrique-Silva F.
Mutational analyses of the signals involved in the subcellular location of DSCR1. BMC Cell Biol. 2002 Sep 11;3(1):24.

3. Wang Y, De Keulenaer GW, Weinberg EO, Muangman S, Gualberto A, Landschulz KT, Turi TG, Thompson JF, Lee RT. Direct biomechanical induction of endogenous calcineurin inhibitor Down Syndrome Critical Region-1 in cardiac myocytes. Am J Physiol Heart Circ Physiol. 2002 Aug;283(2):H533-9.

4. Gorlach J, Fox DS, Cutler NS, Cox GM, Perfect JR, Heitman J.
Identification and characterization of a highly conserved calcineurin binding protein, CBP1/calcipressin, in Cryptococcus neoformans. EMBO J.
2000 Jul 17;19(14):3618-29.

5. Schuchmann S, Heinemann U. Diminished glutathione levels cause spontaneous and mitochondria-mediated cell death in neurons from trisomy 16 mice: a model of Down's syndrome. J Neurochem 2000;74(3):1205-14.

6. Schuchmann S, Muller W, Heinemann U. Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
J Neurosci 1998;18(18):7216-31.


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